小儿喉状瘤病中医病证

目的中医在治疗小儿喉状瘤病的过程中,有一定的优势,其可在术后有效地制约并发症的发生,并在一定程度上降低了本病的复发。但祖国医学介入本病诊疗时间不长,在临床报道中,缺乏大样本对比观察,而针对小儿特殊体质的中医治疗策略也显不足。本研究是在中医药管理局青年科学研究资助项目支持下,旨在通过对古代典籍及现代文献的研究,挖掘对JORRP具有指导意义的中医的理论,并通过大样本、全证候域的证候临床调查,初步确立本病的中医主要临床证型,并较全面地浅析浅析本病相关因素的规律,同时观察“专方”对JORRP疾病进程的影响和临床疗效。策略理论研究1通过对古代典籍的查阅与浅析浅析,系统浅析浅析本病的“中医命名”与“喉科”及“小儿科”特色理论在本病中的应用。2通过对本病现代研究的回顾性浅析浅析,归纳小儿喉状瘤病常见中医证候的分布特点。3通过对“专方”的拆分剖析,从整体上把握其基本方义和主要治法。临床研究1对116例患儿进行中医症状调查(包括症状、体征),并通过软件建立数据库,进行多种因素(年龄、性别、发病季节、地域等)的分层研究。2对116例患儿的症状进行初步浅析浅析,并应用“症状加权积分法”,对116例数据,进行浅析浅析,初步论述本病的主要证型。3将116例患儿随机分成治疗组与对照组,通过比较两组患儿的治疗效果,进一步浅析浅析JORRP的证侯规律。结果理论研究1在对古代文献研究的基础上,初步将本病释名为“喉蕈”,并总结“喉属肺”和“胎毒”理论的源流以及在本病治疗中的应用。2以现代文献研究为基础,确立本病的主要病机,并确定“前、中、后三期”分型论治的治疗策略,以此设立“专方”,进行中医药辅助治疗。临床研究1进行相关因素浅析浅析后发现:①患儿性别差异并不十分明显;②首发年龄的峰值,出现在1岁和3岁;③患儿的平均发病天数,多集中在1-3个月,以30天居多;④发病的分布区域,多集中在经济欠发达省份的区县和乡村地区,如河南省、江西省、湖北省和山西省。2从具体数据浅析浅析提示:本病的证型分布,按频次由高至低依此为:痰瘀互阻(23.28%)、痰湿阻滞(19.83%)、气滞痰凝(16.38%)、肺气虚损(12.07%)、脾气虚损(9.48%)、血瘀气滞(8.62%)、阴虚火旺(6.90%)、风寒袭肺(1.72%)和风热袭肺(1.72%)。3通过两组数据的比较,可初步推论:治疗组与对照组的平均复发天数具有显著性差异。对照组平均复发天数为31.88天,治疗组平均复发天数为38.96天,说明复发天数延长,中药对于辅助治疗术后小儿状瘤病,有一定的疗效。结论理论研究1由于中医喉科自古至今,对于一病的命名,就纷繁冗杂,故对于本病,则以其突出的体征作为命名依据,终以“喉蕈”命名,较为合理。2“喉属肺”和“胎毒”理论,是对本病病因病机的阐释和治疗策略的拓展,既是尊古,又是创新。3利用前、中、后三期分型论治的策略,从整体上把握了本病发展的主要规律,为“主方”的确立以及《小儿复发性喉状瘤病中医诊疗草案》的制定,创造了基础。临床研究1通过对116例患儿,进行临床流行病学横断面调查发现:其流行病分布特点,与国外报道有一定的差异,突出特点为:首发年龄偏早,平均复发天数较短。其主要理由是:由于本国经济水平较发达国家落后,防病治病意识较淡,如,无论是母亲在怀孕期间身染尖锐湿疣病毒,而未及时医治,传染婴儿,还是出生后婴儿的接种以及护理的不健全,都可造成本病的发生。2对9种证型的初步浅析浅析,认为本病以“虚实错杂”为主,证型繁复。其中,实邪多为“气,血,痰,湿”;虚证,多责之于“肺、脾”二脏。然而,小儿状瘤病发病时,常以相兼证型出现。其理由有三:首先,小儿的特殊体质;其次,病程较长,易于复发;最后,本病病位在咽喉,为多经循行之要道,病发时,可引起多脏受累,故兼症百出。3通过对中药辅助治疗本病的疗效观察,笔者认为,“专方”具有:一、祛除痰瘀;二、保护真硕士论文网;三、益气行气;四、顾护阴精的作用,并结合“以方测证”的理论,推知本病的主要症结就在于“痰瘀互结,气阴耗损”。故本方既针对状瘤的特殊病证,、又考虑到小儿的特殊体质,以辨病为先,分型论治为后,达到了中医“标本兼顾”的治疗理念。

【Abstract】wWw.shuoshilunwen.com ObjectiveTraditional Chinese Medicine Treatment of JORRP, has its advantages, which can be effective control of postoperative complications, and to some extent, reduce the recurrence of the disease. But the Chinese medicine treatment of this disease has not been long and the lack of large sample comparative study in the clinical reports, while the methods for the treatment of children with special physical he been increasingly inadequate. This study was conducted in Traditional Chinese Medicine Research funded projects supported young people. It sought the guiding significance JORRP Chinese medicine theory by studying the ancient classics and modern literature. And through the whole syndrome of clinical syndromes domain preliminary investigations in a large sample, it could get the main clinical syndromes of TCM, and make a more comprehensive analysis of disease-related factors in children, while observing the "Special Prescription " to effects ahbout the disease process and its clinical efficacy. And the essay analyzed the main syndromes of this disease and its causes and pathogenesis through the" syndrome differentiation through formula effect asesent " approach.MethodsTheoretical study1 Had analyzed ancient texts, this essay systematically reviews on this disease’s " TCM Naming School " and " laryngology and pediatric of characteristic theory" in this disease applications.2 Through a retrospective analysis of modern study of this disease, it get the common feature of traditional Chinese medicine syndromes in the distribution.3 By the analysis of" Special Prescription ", this essay could get to grasp its "construction of formular " and the main treatment.Clinical study1 This essay has made the "symptom investigation" about 116 cases of JORRP (including the symptoms and signs) and established a database, so to carry out a variety of factors (age, sex, incidence of the season, geography, etc.).2 Applicating the "symptom-weighted integral method", it has received preliminary discussion of the main syndromes of this disease3 The 116 cases were randomly divided into treatment group and control group, comparing two groups of children with treatment and further analyzing the rule.ResultsTheoretical study1 Based on the study of ancient literature, JORRP will be known as "throat mushroom", and it concluded the origins of "throat relate to lung" and "Tai Du" theory, so as to treat this disease.2 this essay has established the main pathogenesis of this disease and divided its process into "before, during and after" three terms, so to set up a " Special Prescription "to carry out this disease in the adjuvant treatment of Chinese medicine.Clinical study1 "Associated Factor Analysis" found that:①children with gender differences are not very clear;②the peak of "Starting Age" appeared in the 1-year-old and 3-year-old;③the incidence of children with an erage of days concentrated in 1-3 months, to 30 days mostly;④the geographic distribution of this disease, mostly concentrated in economically underdeveloped provinces(including counties and rural areas), such as Henan, Jiangxi, Hubei and Shanxi Province.2 The specific data suggests that:the distribution of the disease syndromes, according to frequency of high to low, are as follows:(1)blood-tinged sputum(23.28%), (2)stagnation of phlegm-damp(19.83%), (3)qi stasis(16.38%), (4) deficiency of lung qi (12.07%), (5) deficiency of spleen qi (9.48%), (6) qi and blood stasis(8.62%), (7)flaring of fire due to yin deficiency(6.90%), (8)wind-cold tightening the lung(1.72%), (9)wind-heat tightening the lung (1.72%).3 The result points out:two groups of data he a significant difference. The erage number of days in the control group is 31.88 days, the treatment group the erage number of days is 38.96 days. They indicated the number of days has extended. There is a certain effect. About the TCM for the adjuvant treatment of JORRP.ConclusionsTheoretical study1 This essay uses the signs of its prominent as a named basis, and finally named as "throat mushroom". It is more reasonable.2 " Throat related to lung " and "Tai Du" theory, is the cause of the disease and the expansion about treatment of the interpretation. They are Both ancient statues but also innovations.3 Using three terms on the method of treatment, doctors grasp of the major development of this disease, Meanwhile, they he created a foundation for the establishment of " Special Prescription " and《the TCM treatment of JORRP (draft)》.Clinical study1 The clinical epidemiological cross-sectional survey found that:There were some differences between the epidemic characteristics of China and foreign reports. The prominent characteristics are as follows:①"Starting Age" is early;②the erage number of days is shorter. The main reason is:The level of China’s economies behinds more developed countries. Therefore the people are much little aware of prevention and cure. For example,the mother during pregnancy infected with condyloma virus, without timely medical treatment. The infants they infected is JORRP. And the baby after birth vaccination as well as the care is not perfect. With the distribution of children in China, mostly in economically underdeveloped provinces, is the same proof of this reason.2 Analyzing the nine kinds of syndrome, this essay suggests that the" pattern of deficiency-excess complex" is the main syndrome. The excess evil included "qi, blood, sputum, wet"; the deficiency evil relied on "lungs, spleen". However, the process of JORRP often appears accompanying symptoms.3 The author believes that:the main cause of this disease is " syndrome of intermingled phlegm and blood stasis, Qi and Yin deficiency", combined with the theory about " syndrome differentiation through formula effect asesent ". Therefore, this prescription for the JORRP, taking into account on children with special physical. It distinguished patients firstly and has treatment based on syndrome differentiation secondly. It has met "treating both the branch and the root simultaneously".

【关键词】 小儿;喉状瘤;中医;证侯;
【Key words】 Children;Papilloma of Larynx;TCM;Syndrome;

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